General Information

  • ID:  hor000255
  • Uniprot ID:  NA
  • Protein name:  Pigment-dispersing hormone
  • Gene name:  NA
  • Organism:  Ocypode ceratophthalma
  • Family:  Arthropod PDH family
  • Source:  animal
  • Expression:  brain, eyestalk ganglia and sinus gland
  • Disease:  NA
  • Comments:  NA
  • Taxonomy:  NA
  • GO MF:  NA
  • GO BP:  NA
  • GO CC:  NA

Sequence Information

  • Sequence:  NSELINSILGLPKVMNDA
  • Length:  18
  • Propeptide:  NA
  • Signal peptide:  NA
  • Modification:  NA
  • Glycosylation:  NA
  • Mutagenesis:  NA

Activity

  • Function:  Induces light-adaptive movement of pigment in distal eye pigment cells and?pigment dispersion
  • Mechanism:  NA
  • Cross BBB:  NO
  • Target:  NA
  • Target Unid:  NA
  • IC50: NA
  • EC50: NA
  • ED50: NA
  • kd: NA
  • Half life: NA

Structure

  • Disulfide bond:  NA
  • Structure ID:  NA
  • Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)
  •    hor000255_AF2.pdbhor000255_ESM.pdb

Physical Information

Mass: 223165 Formula: C83H142N22O28S
Absent amino acids: CFHQRTWY Common amino acids: LN
pI: 4.18 Basic residues: 1
Polar residues: 6 Hydrophobic residues: 7
Hydrophobicity: 18.33 Boman Index: -1406
Half-Life: 1.4 hour Half-Life Yeast: 3 min
Half-Life E.Coli: >10 hour Aliphatic Index 130
Instability Index: 3582.78 Extinction Coefficient cystines: 0
Absorbance 280nm: 0

Literature

  • PubMed ID:  23298572
  • Title:  Mass Spectrometric Characterization of the Neuropeptidome of the Ghost Crab Ocypode Ceratophthalma (Brachyura, Ocypodidae)